This pattern is characterized by decorated cytoskeletal fibers, sometimes with small, discontinuous granular deposits. Typical staining show striated actin cables spanning the long axis of the cells. e.g. anti-actin, anti-non-muscle myosin.

Staining of microtubules and intermediate filaments spreading from the nuclear rim. e.g. anti-cytokeratin, anti-vimentin, anti-tropomyosin.

Enhanced decoration of short segments, periodic dense bodies, along the stress fibers. e.g. anti-alpha-actinin, anti-vinculin.                        

Staining of GW bodies in the cytoplasm of interphase cells with high numbers in late S/G2 cells. e.g. anti-GW182, anti-Su/Ago2.                        

The pattern appears cloudy, almost homogeneous throughout the cytoplasm. e.g. anti-PL-7.                        

Scattered small speckles in the cytoplasm mostly with homogeneous or dense fine speckled background. e.g. anti-Jo-1.                        

Coarse granular filamentous staining extending throughout the cytoplasm. e.g. anti-mitochondrial antibodies.                        

Discontinuous speckled or granular perinuclear ribbon-like staining with polar distribution in the cytoplasm. e.g. anti-giantin, anti-golgin-245.                        

 Distinct rod and ring structures in the cytoplasm of interphase cells. Some smaller rods and rings also reported in the nucleus.